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Cancer Supportive and Survivorship Care Programs Improving Quality of Life Logo Natalie Ledesma, MS, RD
Cancer Resource Center
UCSF Comprehensive Cancer Center
University of California, San Francisco

Books, Cookbooks, Newsletters
Nutrition and Prostate Cancer
High-Fiber Sources

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The ABC's of Nutrition & Supplements and Prostate Cancer -written by Mark Moyad
Eating Your Way to Better Health: The Prostate Forum Nutrition Guide -written by Charles E. Myers Jr., M.D., Sara Sgarlat
Steck, R.T. and Rose Sgarlat Myers, PT., Ph.D.
Food for Life: How the New Four Food Groups Can Save Your Life -written by Neal Barnard, M.D.
How to Prevent & Treat Cancer with Natural Medicine -written by Michael Murray, N.D.
The Color Code -written by James Joseph, Ph.D., Daniel Nadeau, M.D., & Anne Underwood
The Prostate Cancer Protection Plan -written by Robert Arnot, M.D.

Cookbooks Cancer Lifeline Cookbook: Good Nutrition, Recipes, and Resources to Optimize the Lives of People Living with Cancer -written by Kimberly Mathai & Ginny Smith
Fat-Free and Easy: Great Meals in Minutes -written by Jennifer Raymond (vegetarian cookbook)
Lickety-Split Meals -written by Zonya Foco, R.D. One Bite at a Time: Nourishing Recipes for People with Cancer, Survivors, & Their Caregivers -written by Rebecca Katz,
Marsha Tomassi, & Mat Edelson The Peaceful Palate -written by Jennifer Raymond (vegetarian cookbook)


Cooking Light
Environmental Nutrition (800) 829-5384
Nutrition Action Health Letter Fax: (202) 265-4954

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American Cancer Society (415) 394-7100
American Institute for Cancer Research (800) 843-8114
Cancer Nutrition Info (Provides up-to-date & comprehensive information on the connection between nutrition & cancer)
Cancer Supportive Care - Educational modules to complement surgery, radiation, chemotherapy, hormonal therapy and immunotherapy
CaP CURE - Good source of current research and articles. Center for Informed Food Choices - Offer cooking classes in the Bay Area that emphasize plant-based foods.
Consumer Lab - Evaluates quality of over-the-counter supplements
Doctor's Guide to Prostate Cancer
EarthSave International - Promotes food choices that are healthy for people & the planet.
Ida & Joseph Friend Cancer Resource Center -UCSF Mt.Zion (415) 885-3693
National Cancer Institute (800) 4-CANCER (800-422-6237)
Oncolink -Provides information regarding clinical trials, newsgroups, psychosocial support, & more.
Physicians Committee for Responsible Medicine -Nonprofit organization that promotes preventive medicine, conducts clinical research, and encourages higher standards for ethics & effectiveness in research.
Prostate Pointers - Comprehensive prostate cancer web site with a full range of subjects pertinent to prostate cancer.
San Francisco Vegetarian Society -Monthly restaurant outings & pot-luck dinners; call 415-273-5481.
US TOO International, Inc. - Nonprofit organization offers descriptions of treatments, online newsletter, glossary of medical terms & information on local support groups.
The Vegetarian Resource Group - Provides vegetarian nutrition information & vegetarian recipes

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1. Heber, D., Fair, W., & Ornish, D. Capcure. (1999). Nutrition & Prostate Cancer: A Monograph from the CaP CURE Nutrition Project. 2nd edition. January
2. Byers, T, Nestle, M, McTiernan, A, Doyle, C, Currie-Williams, A, Gansler, T, et al. American Cancer Society 2001 Nutrition and Physical Activity Guidelines Advisory Committee. (2002). American Cancer Society guidelines on nutrition and physical activity for cancer prevention: Reducing the risk of cancer with healthy food choices and physical activity. CA: A Cancer Journal for Clinicians, 52(2), 92-119.
3. Khaw, K.T., Bingham, S., Welch, R.L.A., Wareham, N., Oakes, S., Day, N., et al. (2001). The European Prospective Investigation into Cancer and Nutrition. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. Lancet, 357, 657-663.
4. Willett, W.C. (2000). Intakes of fruits, vegetables and related nutrients and the risk of non-Hodgkin's lymphoma among women. Cancer Epidemiology Biomarkers and Prevention, 9, 477-485.
5. U.S. Dept. of Agriculture. (1995). Nutrition and your health: Dietary Guidelines for Americans, ed. 4, Home & Garden Bulletin No. 232, Washington DC, U.S. Dept. of Health and Human Services.
6. World Cancer Research Fund/American Institute for Cancer Research. Food, nutrition and the prevention of cancer: A global perspective. Washington, DC: American Institute for Cancer Research, 1997.
7. Steinmetz, K.A., & Potter, J.D. (1996). Vegetables, fruit, and cancer prevention: a review. Journal of American Dietetic Association, 96, 1027-1039.
8. Zhang, S., Hunter, D.J., Forman, M.R., Rosner, B.A., Speizer, F.E., Colditz, G.A., et al. (1999). Dietary carotenoids and vitamins A, C, and E and risk of breast cancer. Journal of the National Cancer Institute, 91, 547-556.
9. Zhang, S.M., Hunter, D.J., Rosner, B.A., Giovannucci, E.L., Colditz, G.A., Speizer, F.E., et al. (2000). Intakes of fruits, vegetables, and related nutrients and the risk of non-Hodgkin's lymphoma among women. Cancer Epidemiology Biomarkers and Prevention, 9(5), 477-485.
10. Freudenheim, J.L., Marshall, J.R., Vena, J.E., Laughlin, R., Brasure, J.R., Swanson, M.K., et al. (1996). Premenopausal breast cancer risk and intake of vegetables, fruits, and related nutrients. Journal of the National Cancer Institute, 88, 340-348.
11. Rock, Cl., Saxe, G.A., Ruffin, M.T. 4th, August, D.A, & Schottenfeld, D. (1996). Carotenoids, vitamin A, and estrogen receptor status in breast cancer. Nutrition and Cancer,25(3), 281-296.
12. Eastwood, M.A. (1999). Interaction of dietary antioxidants in vivo: How fruit and vegetables prevent disease? Quarterly Journal of Medicine, (92), 527-530.
13. Voorrips, L.E., Goldbohm, R.A., Brants, H.A., van Poppel, G.A., Sturmans, F., Hermus, R.J., et al. (2000). A prospective cohort study on antioxidant and folate intake and male lung cancer risk. Cancer Epidemiology Biomarkers and Prevention, 9, 357-365.
14. Hodge, A.M., English, D.R., McCredie, M.R., Severi, G., Boyle, P., Hopper, J.L., et al. (2004). Foods, nutrients and prostate cancer. Cancer Causes Control, 15(1), 11-20.`
15. Cohen, J.H., Kristal, A.R., & Stanford, J.L. (2000). Fruit and vegetable intakes and prostate cancer risk. Journal of the National Cancer Institute, 92(1), 61-68.
16. Jain, M.G., Hislop, G.T., Howe, G.R., & Ghadirian, P. (1999). Plant foods, antioxidants, and prostate cancer risk: findings from casecontrol studies in Canada. Nutrition and Cancer, 34(2), 173-184.
17. Deneo-Pellegrini, H., De Stefani, E., Ronco, A., & Mendilaharsu, M. (1999). Foods, nutrients and prostate cancer: a case-control study in Uruguay. British Journal of Cancer, 80(3-4), 591-597.
18. Wang, L., Liu, D., Ahmed, T., Chung, F.L., Conaway, C., Chiao, J.W., et al. (2004). Targeting cell cycle machinery as a molecular mechanism of sulforaphane in prostate cancer prevention. International Journal of Oncology, 24(1), 187-192.
19. Kolonel, L.N., Hankin, J.H., Whittemore, A.S., Wu, A.H., Gallagher, R.P., Wilkens, L.R., et al. (2000). Vegetables, fruits, legumes and prostate cancer: a multiethnic case-control study. Cancer Epidemiology Biomarkers Prevention, 9(8), 795-804.
20. Chinni, S.R., Li, Y., Upadhyay, S., Koppolu, P.K., Sarkar, F.H. (2001). Indole-3-carbinol (I3C) induced cell growth inhibition, G1 cell cycle arrest and apoptosis in prostate cancer cells. Oncogene, 20(23), 2927-2936.
21. Bosetti, C., Tzonou, A., Lagiou, P., Negri, E., Trichopoulos, D., & Hsieh, C.C., et al. (2000). Fraction of prostate cancer incidence attributed to diet in Athens, Greece. European Journal of Cancer Prevention, 9(2), 119-123.
22. Norrish, A.E., Jackson, R.T., Sharpe, S.J., & Skeaff, C.M. (2000). Prostate cancer and dietary carotenoids. American Journal of Epidemiology, 151(2), 119-123.
23. Mills, P.K., Beeson, W.L., Phillips, R.L., & Fraser, G.E. (1989). Cohort study of diet, lifestyle, and prostate cancer in Adventist men. Cancer, 64(3), 598-604.
24. Tzonou, A., Signorello, L.B., Lagiou, P., Wuu, J., Trichopoulos, D., & Trichopoulou, A. (1999). Diet and cancer of the prostate: a case-control study in Greece. International Journal of Cancer, 80(5), 704-708.
25. Giovannucci, E., Ascherio, A., Rimm, E.B., Stampfer, M.J., Colditz, G.A., Willett, W.C., et al. (1995). Intake of carotenoids and retinol in relation to risk of prostate cancer. Journal of the National Cancer Institute, 87(23), 1767-1776.
26. Wu, K., Erdman, J.W. Jr, Schwartz, S.J., Platz, E.A., Leitzmann, M., Clinton, S.K., et al. (2004). Plasma and Dietary Carotenoids, and the Risk of Prostate Cancer: A Nested Case-Control Study. Cancer Epidemiology Biomarkers and Prevention, 13(2), 260-269.
27. Key, T.J., Silcocks, P.B., Davey, G.K., Appleby, P.N., & Bishop, D.T. (1997). A case-control study of diet and prostate cancer. British Journal of Cancer, 76(5), 678-687.
28. Ohno, Y., Yoshida, O., Oishi, K., Okada, K., Yamabe, H., Schroeder, F.H., et al. (1998). Dietary beta-carotene and cancer of the prostate: a case-control study in Kyoto, Japan. Cancer Research, 48(5), 1331-1336.
29. Lombardi-Boccia, G., Lucarini, M., Lanzi, S., Aguzzi, A., & Cappelloni, M. (2004). Nutrients and antioxidant molecules in yellow plums (Prunus domestica L.) from conventional and organic productions: a comparative study. Journal of Agricultural Food Chemistry, 52(1), 90-94.
30. Grinder-Pedersen, L., Rasmussen, S.E., Bugel, S., Jorgensen, L.V., Dragsted, L.O., et al. (2003). Effect of diets based on foods from conventional versus organic production on intake and excretion of flavonoids and markers of antioxidative defense in humans. Journal of Agricultural Food Chemistry, 51(19), 5671-5676.
31. Asami, D.K., Hong, Y.J., Barrett, D.M., & Mitchell, A.E. (2003). Comparison of the total phenolic and ascorbic acid content of freeze-dried and air-dried marionberry, strawberry, and corn grown using conventional, organic, and sustainable agricultural practices. Journal of Agricultural Food Chemistry, 51(5), 1237-1241.
32. Pierce, J.P., Faerber, S., Wright, F.A., Rock, C.L., Newman, V., Flatt, S.W., et al. (2002). A randomized trial of the effect of a plant-based dietary pattern on additional breast cancer events and survival: the Women's Healthy Eating and Living (WHEL) Study. Controlled Clinical Trials, 23(6), 728-756.
33. Harris, P.J., Roberton, A.M., Watson, M.E., Triggs, C.M., & Ferguson, L.R. (1993). The effects of soluble-fiber polysaccharides on the adsorption of a hydrophobic carcinogen to an insoluble dietary fiber. Nutrition and Cancer, 19(1), 43-54.
34. Tariq, N., Jenkins, D.J., Vidgen, E., Fleshner, N., Kendall, C.W., Story, J.A., et al. (2000). Effect of soluble and insoluble fiber diets on serum prostate specific antigen in men. Journal of Urology, 163(1), 114-118.
35. Tymchuk, C.N., Barnard, R.J., Heber, D., & Aronson, W.J. (2001). Evidence of an inhibitory effect of diet and exercise on prostate cancer cell growth. The Journal of Urology, 166(3), 1185-1189.
36. Slavin, JL. (2000). Mechanisms for the impact of whole grain foods on cancer risk. Journal of the American College of Nutrition, 19(3 Suppl), 300S-307S.
37. Pelucchi, C., Talamini, R., Galeone, C., Negri, E., Franceschi, S., Dal Maso, L., et al. (2004). Fibre intake and prostate cancer risk. International Journal of Cancer, 109(2), 278-280.
38. La Vecchia, C., Chatenoud, L., Negri, E., & Franceschi, S. (2003). Session: whole cereal grains, fibre and human cancer wholegrain cereals and cancer in Italy. The Proceedings Nutrition Society, 62(1), 45-49.
39. Shike, M., Latkany, L., Riedel, E., Fleisher, M., Schatzkin, A., Lanza, E., et al. (2002). Lack of effect of a low-fat, high-fruit, -vegetable, and - fiber diet on serum prostate-specific antigen of men without prostate cancer: results from a randomized trial. Journal of Clinical Oncology, 20(17), 3592-3598.
40. Hebert, J.R., Hurley, T.G., Olendzki, B.C., Teas, J., Ma, Y., Hampl, J.S., et al. (1998). Nutritional and socioeconomic factors in relation to prostate cancer mortality: a cross-national study. Journal of the National Cancer Institute, 90, 1637-1647.
41. Williams, G.M., Williams, C.L., & Weisburger, J.H. (1999). Diet and cancer prevention: the fiber first diet. Toxicological Sciences, 52(2 Suppl), 72-86.
42.Spentzos, D., Mantzoros, C., Regan, M.M., Morrissey, M.E., Duggan, S., Flickner-Garvey, S., et al. (2003). Minimal effect of a lowfat/ high soy diet for asymptomatic, hormonally naive prostate cancer patients. Clinical Cancer Research, 9(9), 3282-3287.
43. Habito, R.C., & Ball, M.J. (2001). Postprandial changes in sex hormones after meals of different composition. Metabolism, 50(5), 505-511.
44. Fleshner, N., Bagnell, P.S., Klotz, L., & Venkateswaran, V. (2004). Dietary fat and prostate cancer. The Journal of Urology, 171(2 Pt 2), S19-S24.
45. Veierod, M.B., Laake, P., & Thelle, D.S. (1997). Dietary fat intake and risk of prostate cancer: a prospective study of 25,708 Norwegian men. International Journal of Cancer, 73(5), 634-638.
46. Bairati, I., Meyer, F., Fradet, Y., & Moore, L. (1998). Dietary fat and advanced prostate cancer. The Journal of Urology, 159(4), 1271-1275.
47. Meyer, F., Bairati, I., Shadmani, R., Fradet, Y., & Moore, L. (1999). Dietary fat and prostate cancer survival. Cancer Causes Control, 10(4), 245- 251.
48. Le Marchand, L., Hankin, J.H., Kolonel, L.N., & Wilkens, L.R. (1991). Vegetable and fruit consumption in relation to prostate cancer risk in Hawaii: a reevaluation of the effect of dietary beta-carotene. American Journal of Epidemiology, 133(3), 215-219.
49. Giovannucci, E., Rimm, E.B., Colditz, G.A., Stampfer, M.J., Ascherio, A., Chute, C.C., et al. (1993). A prospective study of dietary fat and risk of prostate cancer. Journal of the National Cancer Institute, 85(19), 1571-1579.
50. Lee, M.M., Wang, R.T., Hsing, A.W., Gu, F.L., Wang, T., Spitz, M., et al. (1998). Case-control study of diet and prostate cancer in China. Cancer Causes Control. 9(6), 545-552.
51. Kushi, L., & Giovannucci, E. (2002). Dietary fat and cancer. The American Journal of Medicine, 113 Suppl 9B, 63S-70S.
52. Meyer, F., Bairati, I., Fradet, Y., & Moore, L. (1997). Dietary energy and nutrients in relation to preclinical prostate cancer. Nutrition Cancer, 29(2), 120-126.
53. Fradet, Y, Meyer, F, Bairati, I, Shadmani, R, & Moore, L. Dietary fat and prostate cancer progression and survival. European Urology, 35(5- 6), 388-391.
54. Michaud, D.S., Augustsson, K., Rimm, E.B., Stampfer, M.J., Willett, W.C., Giovannucci, E., et al. (2001). A prospective study on intake of animal products and risk of prostate cancer. Cancer Causes Control, 12(6), 557-567.
55. Ramon, J.M., Bou, R., Romea, S., Alkiza, M.E., Jacas, M., Ribes, J., et al. (2000). Dietary fat intake and prostate cancer risk: a casecontrol study in Spain. Cancer Causes Control, 11(8), 679-685.
56. Lemaitre, R.N., King, I.B., & Raghunathan, T.E. (2002). Cell membrane trans-fatty acids and the risk of primary cardiac arrest. Circulation, 105, 697-701.
57. Katan, MB. (2000). Trans fatty acids and plasma lipoproteins. Nutrition Reviews, 58, 188-191.
58. Mensink R.P., & Katan M.B. (1990). Effect of dietary trans fatty acids on high-density and low-density lipoprotein cholesterol levels in healthy subjects. New England Journal of Medicine, 323, 439-445.
59. Nelson, GJ. (1998). Dietary fat, trans fatty acids, and risk of coronary heart disease. Nutrition Reviews, 56, 250-252.
60. Bakker, N., Van't, Veer, P., & Zock, P.L. (1997). Adipose fatty acids and cancers of the breast, prostate and colon: an ecological study. EURAMIC Study Group. International Journal of Cancer, 72(4), 587-591.
61. Slattery, M.L., Benson, J., Ma, K.N., Schaffer, D., & Potter, J.D. (2001). Trans-fatty acids and colon cancer. Nutrition and Cancer, 39(2), 170-175.
62. Newcomer, L.M., King, I.B., Wicklund, K.G., & Stanford, J.L. (2001). The association of fatty acids with prostate cancer risk. Prostate, 47(4), 262-268.
63. Hughes-Fulford, M., Chen, Y., & Tjandrawinata, R.R. (2001). Fatty acid regulates gene expression and growth of human prostate cancer PC-3 cells. Carcinogenesis, 22(5), 701-707.
64. Godley, P.A., Campbell, M.K., Gallagher, P., Martinson, F.E., Mohler, J.L., Sandler, R.S., et al. (1996). Biomarkers of essential fatty acid consumption and risk of prostatic carcinoma. Cancer Epidemiology Biomarkers and Prevention, 5(11), 889-895.
65. Ghosh, J., & Myers, C.E. (1997). Arachidonic acid stimulates prostate cancer cell growth: critical role of 5-lipoxygenase. Biochemical Biophysical Research Communications, 235(2), 418-423.
66. Mannisto, S., Pietinen, P., Virtanen, M.J., Salminen, I., Albanes, D., Giovannucci, E., Virtamo, J., et al. (2003). Fatty acids and risk of prostate cancer in a nested case-control study in male smokers. Cancer Epidemiology Biomarkers and Prevention, 12(12), 1422-1428.
67. Harvei, S., Bjerve, K.S., Tretli, S., Jellum, E., Robsahm, T.E., Vatten, L., et al. (1997). Prediagnostic level of fatty acids in serum phospholipids: omega-3 and omega-6 fatty acids and the risk of prostate cancer. International Journal of Cancer, 71(4), 545-551.
68. Gann, P.H., Hennekens, C.H., Sacks, F.M., Grodstein, F., Giovannucci, E.L., Stampfer, M.J., et al. (1994). Prospective study of plasma fatty acids and risk of prostate cancer. Journal of the National Cancer Institute, 86(4), 281-286.
69. Norrish, A.E., Jackson, R.T., Sharpe, S.J., & Skeaff, C.M. (2000). Men who consume vegetable oils rich in monounsaturated fat: their dietary patterns and risk of prostate cancer (New Zealand). Cancer Causes Control, 11(7), 609-615.
70. Norrish, A.E., Skeaff, C.M., Arribas, G.L., Sharpe, S.J., & Jackson, R.T. (1999). Prostate cancer risk and consumption of fish oils: a dietary biomarker-based case-control study. British Journal of Cancer, 81(7), 1238-1242.
71. Augustsson, K., Michaud, D.S., Rimm, E.B., Leitzmann, M.F., Stampfer, M.J., Willett, W.C., et al. (2003). A prospective study of intake of fish and marine fatty acids and prostate cancer. Cancer Epidemiology Biomarkers and Prevention, 12(1), 64-67.
72. Terry, P., Lichtenstein, P., Feychting, M., Ahlbom, A., & Wolk, A. (2001). Fatty fish consumption and risk of prostate cancer. Lancet, 357(9270), 1764-1766.
73. Terry, P.D., Rohan, T.E., & Wolk, A. (2003). Intakes of fish and marine fatty acids and the risks of cancers of the breast and prostate and of other hormone-related cancers: a review of the epidemiologic evidence. The American Journal of Clinical Nutrition, 77(3), 532-543.
74. Chung, B.H., Mitchell, S.H., Zhang, J.S., & Young, C.Y. (2001). Effects of docosahexaenoic acid and eicosapentaenoic acid on androgenmediated cell growth and gene expression in LNCaP prostate cancer cells. Carcinogenesis, 22(8), 1201-1206.
75. Harris, P.J., Roberton, A.M., Watson, M.E., Triggs, C.M., & Ferguson, L.R. (1993). The effects of soluble-fiber polysaccharides on the adsorption of a hydrophobic carcinogen to an insoluble dietary fiber. Nutrition and Cancer, 19(1), 43-54.
76. Davis, B.C., & Kris-Etherton, P.M. (2003). Achieving optimal essential fatty acid status in vegetarians: current knowledge and practical implications. American Journal of Clinical Nutrition, 78(3 Suppl), 640S-646S.
77. Gerster, H. (1998). Can adults adequately convert alpha-linolenic acid (18:3n-3) to eicosapentaenoic acid (20:5n-3) and docosahexaenoic acid (22:6n-3)? International Journal for Vitamin and Nutrition Research, 68(3), 159-173.
78. Andersson, S.O., Wolk, A., Bergstrom, R., Giovannucci, E., Lindgren, C., Baron, J., et al. (1996). Energy, nutrient intake and prostate cancer risk: a population-based case-control study in Sweden. International Journal of Cancer, 68(6), 716-722.
79. De Stefani, E., Deneo-Pellegrini, H., Boffetta, P., Ronco, A., & Mendilaharsu, M. (2000). Alpha-linolenic acid and risk of prostate cancer: a case-control study in Uruguay. Cancer Epidemiology Biomarkers and Prevention, 9(3), 335-338.
80. Hsing, A.W., Chua, S. Jr., Gao, Y.T., Gentzschein, E., Chang, L., Deng, J., et al. (2001). Prostate cancer risk and serum levels of insulin and leptin: a population-based study. Journal of the National Cancer Institute. May 93(10), 783-789.
81. Barnard, R.J., Ngo, T.H., Leung, P.S., Aronson, W.J., & Golding, L.A. (2003). A low-fat diet and/or strenuous exercise alters the IGF axis in vivo and reduces prostate tumor cell growth in vitro. Prostate, 56(3), 201-206.
82. Ngo, T.H., Barnard, R.J., Tymchuk, C.N., Cohen, P., & Aronson, W.J. (2002). Effect of diet and exercise on serum insulin, IGF-I, and IGFBP-1 levels and growth of LNCaP cells in vitro (United States). Cancer Causes Control, 13(10), 929-935.
83. Moyad, M.A. (2003). The use of complementary/preventive medicine to prevent prostate cancer recurrence/progression following definitive therapy: part I--lifestyle changes. Current Opinion in Urology, 13(2), 137-145.
84. Aksoy, Y., Aksoy, H., Bakan, E., Atmaca, A.F., & Akcay, F. (2004). Serum insulin-like growth factor-I and insulin-like growth factor-binding protein-3 in localized, metastasized prostate cancer and benign prostatic hyperplasia. Urologia Internationalis, 72(1), 62-65.
85. Yu, H., & Berkel, H. (1999). Insulin-like growth factors and cancer. Journal of the Louisiana State Medical Society, 151(4), 218-223.
86. Li, L., Yu, H., Schumacher, F., Casey, G., & Witte, J.S. (2003). Relation of serum insulin-like growth factor-I (IGF-I) and IGF binding protein- 3 to risk of prostate cancer (United States). Cancer Causes Control, 14(8), 721-726.
87. Cardillo, M.R., Monti, S., Di Silverio, F., Gentile, V., Sciarra, F., Toscano, V., et al. (2003). Insulin-like growth factor (IGF)-I, IGF-II and IGF type I receptor (IGFR-I) expression in prostatic cancer. Anticancer Research, 23(5A), 3825-3835.
88. Kaaks, R., & Lukanova, A. (2001). Energy balance and cancer: the role of insulin and insulin-like growth factor-I. Proceedings of the Nutrition Society, 60(1), 91-106.
89. Rohan, T.E., Howe, G.R., Burch, J.D., & Jain, M. (1995). Dietary factors and risk of prostate cancer: a case-control study in Ontario, Canada. Cancer Causes Control, 6(2), 145-154.
90. Kristal, A.R., Cohen, J.H., Qu, P., & Stanford, J.L. (2002). Associations of energy, fat, calcium, and vitamin D with prostate cancer risk. Cancer Epidemiology Biomarkers and Prevention, 11(8), 719-725.
91. Hsieh, L.J., Carter, H.B., Landis, P.K., Tucker, K.L., Metter, E.J., Newschaffer, C.J., et al. (2003). Association of energy intake with prostate cancer in a long-term aging study: Baltimore Longitudinal Study of Aging (United States). Urology, 61(2), 297-301.
92. Sonntag, W.E., Lynch, C.D., Cefalu, W.T., Ingram, R.L., Bennett, S.A., Thornton, P.L., et al. (1999). Pleiotropic effects of growth hormone and insulin-like growth factor (IGF)-1 on biological aging: inferences from moderate caloric-restricted animals. The Journal of Gerontology. Series A,
Biological Science & Medical Science, 54(12), B521-B538.
93. Calle. (2003). Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. The New England Journal of Medicine, 348, 1625-1638.
94. Amling, C.L., Riffenburgh, R.H., Sun, L., Moul, J.W., Lance, R.S., Kusuda, L., et al. (2004). Pathologic variables and recurrence rates as related to obesity and race in men with prostate cancer undergoing radical prostatectomy. Journal of Clinical Oncology, 22(3), 439-445.
95. Freedland, S.J., Aronson, W.J., Kane, C.J., Presti, J.C. Jr, Amling, C.L., Elashoff, D., et al. (2004). Impact of obesity on biochemical control after radical prostatectomy for clinically localized prostate cancer: a report by the Shared Equal Access Regional Cancer Hospital database study group. Journal of Clinical Oncology, 22(3), 446-53.
96. Hwang, E.S., & Bowen, P.E. (2002). Can the consumption of tomatoes or lycopene reduce cancer risk? Integrative Cancer Therapies, 1(2), 121-132.
97. Lu, Q.Y., Hung, J.C., Heber, D., Go, V.L., Reuter, V.E., Cordon-Cardo, C., et al. (2001). Inverse associations between plasma lycopene and other carotenoids and prostate cancer. Cancer Epidemiology Biomarkers Prevention, 10(7), 749-756.
98. Gann, P.H., Ma, J., Giovannucci, E., Willett, W., Sacks, F.M., Hennekens, C.H., et al. (1999). Lower prostate cancer risk in men with elevated plasma lycopene levels: results of a prospective analysis. Cancer Research, 59(6), 1225-1230.
99. Kim, H.S., Bowen, P., Chen, L., Duncan, C., Ghosh, L., Sharifi, R., et al. (2003). Effects of tomato sauce consumption on apoptotic cell death in prostate benign hyperplasia and carcinoma. Nutrition and Cancer, 47(1), 40-47.
100. Kucuk, O., Sarkar, F.H., Djuric, Z., Sakr, W., Pollak, M.N., Khachik, F., et al. (2002). Effects of lycopene supplementation in patients with localized prostate cancer. Experimental Biology and Medicine (Maywood), 227(10), 881-885.
101. Bowen, P., Chen, L., Stacewicz-Sapuntzakis, M., Duncan, C., Sharifi, R., Ghosh, L., et al. (2002). Tomato sauce supplementation and prostate cancer: lycopene accumulation and modulation of biomarkers of carcinogenesis. Experimental Biology and Medicine (Maywood), 227(10), 886-893.
102. Chen, L, Stacewicz-Sapuntzakis, M, Duncan, C, Sharifi, R, Ghosh, L, van Breemen, R, et al. (2001). Oxidative DNA damage in prostate cancer patients consuming tomato sauce-based entrees as a whole-food intervention. Journal of the National Cancer Institute, 93(24), 1872- 1879.
103. Weisburger, J.H. (1998). Evaluation of the evidence on the role of tomato products in disease prevention. Proceedings of the Society for Experimental Biology and Medicine, 218(2), 140-143.
104. Boileau, T.W., Liao, Z., Kim, S., Lemeshow, S., Erdman, J.W., Jr, Clinton, S.K. et al. (2003). Prostate carcinogenesis in N-methyl-Nnitrosourea (NMU)-testosterone-treated rats fed tomato powder, lycopene, or energy-restricted diets. Journal of the National Cancer Institute, 95(21), 1578-1586.
105. Corcoran, N.M., Najdovska, M., & Costello, A.J. (2004). Inorganic selenium retards progression of experimental hormone refractory prostate cancer. Journal of Urology, 171(2 Pt 1), 907-910.
106. Sinha, R., & El-Bayoumy, K. (2004). Apoptosis is a Critical Cellular Event in Cancer Chemoprevention and Chemotherapy by Selenium Compounds. Current Cancer Drug Targets, 4(1), 13-28.
107. Clark, L.C., Dalkin, B., Krongrad, A., Combs, G.F. Jr., Turnbull, B.W., Slate, E.H., et al. (1998). Decreased incidence of prostate cancer with selenium supplementation: results of a double-blind cancer prevention trial. British Journal of Urology, 81(5), 730-734.
108. Giovannucci, E., Rimm, E.B., Wolk, A., Ascherio, A., Stampfer, M.J., Colditz, G.A., et al. (1998). Calcium and fructose intake in relation to risk of prostate cancer. Cancer Research, 58(3), 442-447.
109. Yoshizawa, K., Willett, W.C., Morris, S.J., Stampfer, M.J., Spiegelman, D., Rimm, E.B., et al. (1998). Study of prediagnostic selenium level in toenails and the risk of advanced prostate cancer. Journal of the National Cancer Institute, 90(16), 1219-1224.
110. Hartman, T.J., Dorgan, J.F., Woodson, K., Virtamo, J., Tangrea, J.A., Heinonen, O.P., et al. (2001). Effects of long-term alpha-tocopherol supplementation on serum hormones in older men. Prostate, 46(1), 33-38.
111. Brooks, J.D., Metter, E.J., Chan, D.W., Sokoll, L.J., Landis, P., Nelson, et al. (2001). Plasma selenium level before diagnosis and the risk of prostate cancer development. Journal of Urology, 166(6), 2034-2038.
112. Venkateswaran, V., Fleshner, N.E., & Klotz, L.H. (2004). Synergistic effect of vitamin E and selenium in human prostate cancer cell lines. Prostate Cancer Prostatic Disease, 7(1), 54-56.
113. Klein, E.A., Lippman, S.M., Thompson, I.M., Goodman, P.J., Albanes, D., Taylor, P.R., et al. (2003). The selenium and vitamin E cancer prevention trial. World Journal or Urology, 21(1), 21-27.
114. Combs, G.F. Jr., Clark, L.C., & Turnbull, B.W. (1997). Reduction of cancer risk with an oral supplement of selenium. Biomedical Environmental Sciences, 10(2-3), 227-234.
115. Yoshida, M., Sugihara, S., Suenaga, T., Naito, C., Fukunaga, K., Tsuchita, H., et al. (2002). Digestibility and chemical species of selenium contained in high-selenium yeast. Journal of Nutritional Science and Vitaminology (Tokyo), 48(5), 401-404.
116. Schrauzer, G.N. (2001). Nutritional selenium supplements: product types, quality, and safety. Journal of the American College of Nutrition, 20(1), 1-4.
117. Daviglus, M.L., Dyer, A.R., Persky, V., Chavez, N., Drum, M., Goldberg, J., et al. (1996). Dietary beta-carotene, vitamin C, and risk of prostate cancer: results from the Western Electric Study. Epidemiology, 7(5), 472-477.
118. Schuurman, A.G., Goldbohm, R.A., Brants, H.A., & van den Brandt, P.A. (2002). A prospective cohort study on intake of retinol, vitamins C and E, and carotenoids and prostate cancer risk (Netherlands). Cancer Causes Control, 13(6), 573-582.
119. Omenn, G.S., Goodman, G.E., Thornquist, M.D., Balmes, J., Cullen, M.R., Glass, A., et al. (1996). Risk factors for lung cancer and for intervention effects in CARET, the Beta-Carotene and Retinol Efficacy Trial. Journal of the National Cancer Institute, 88(21), 1550-1559.
120. Hennekens, C.H., Buring, J.E., Manson, J.E., Stampfer, M., Rosner, B., Cook, N.R., et al. (1996). Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease. The New England Journal of Medicine, 334(18), 1145-1149.
121. Heinonen, O.P., Albanes, D., Virtamo, J., Taylor, P.R., Huttunen, J.K., Hartman, A.M., et al. (1998). Prostate cancer and supplementation with alpha-tocopherol and beta-carotene: incidence and mortality in a controlled trial. Journal of the National Cancer Institute, 90(6), 440-446.
122. Kristal, A.R., Stanford, J.L., Cohen, J.H., Wicklund, K., & Patterson, R.E. (1999). Vitamin and mineral supplement use is associated with reduced risk of prostate cancer. Cancer Epidemiology Biomarkers and Prevention, 8(10), 887-892.
123. Maramag, C., Menon, M., Balaji, K.C., Reddy, P.G., & Laxmanan, S. (1997). Effect of vitamin C on prostate cancer cells in vitro: effect on cell number, viability, and DNA synthesis. Prostate, 32(3), 188-195.
124. Helzlsouer, K.J., Huang, H.Y., Alberg, A.J., Hoffman, S., Burke, A., & Norkus, E.P., et al. (2000). Association between alpha-tocopherol, gamma-tocopherol, selenium, and subsequent prostate cancer. Journal of National Cancer Institute, 92(24), 2018-2023.
125. Huang, H.Y., Alberg, A.J., Norkus, E.P., Hoffman, S.C., Comstock, G.W., Helzlsouer, K.J., et al. (2003). Prospective study of antioxidant micronutrients in the blood and the risk of developing prostate cancer. American Journal of Epidemiology, 157(4), 335-344.
126. Nomura, A.M., Stemmermann, G.N., Lee, J., & Craft, N.E. (1997). Serum micronutrients and prostate cancer in Japanese Americans in Hawaii. Cancer Epidemiology Biomarkers Prevention, 6(7), 487-491.
127. Chopra, R.K., & Bhagavan, H.N. (1999). Relative bioavailabilities of natural and synthetic vitamin E formulations containing mixed tocopherols in human subjects. International Journal of Vitamin Nutrition Research, 69(2), 92-95.
128. Handelman, G.J., Epstein, W.L., Peerson, J., Spiegelman, D., Machlin, L.J., & Dratz, E.A. (1994). Human adipose alpha-tocopherol and gamma-tocopherol kinetics during and after 1 y of alpha-tocopherol supplementation. American Journal of Clinical Nutrition, 59(5), 1025- 1032.
129. Handelman, G.J., Machlin, L.J., Fitch, K., Weiter, J.J., & Dratz, E.A. (1985). Oral alpha-tocopherol supplements decrease plasma gamma-tocopherol levels in humans. Journal of Nutrition, 115(6), 807-813.
130. Moyad, M.A., Brumfield, S.K., & Pienta, K.J. (1999). Vitamin E, alpha- and gamma-tocopherol, and prostate cancer. Seminars in Urologic Oncology, 17(2), 85-90.
131. Zu, K., & Ip, C. (2003). Synergy between selenium and vitamin E in apoptosis induction is associated with activation of distinctive initiator caspases in human prostate cancer cells. Cancer Research, 63(20), 6988-6995.
132. Jiang, Q., Christen, S., Shigenaga, M.K., & Ames, B.N. (2001). Gamma-tocopherol, the major form of vitamin E in the US diet, deserves more attention. American Journal of Clinical Nutrition, 74(6), 714-722.
133. Galli, F., Stabile, A.M., Betti, M., Conte, C., Pistilli, A., Rende, M., et al. (2004). The effect of alpha- and gamma-tocopherol and their carboxyethyl hydroxychroman metabolites on prostate cancer cell proliferation. Archives of Biochemistry & Biophysics, 423(1), 97-102.
134. Sigounas, G., Anagnostou, A., & Steiner, M. (1997). dl-alpha-tocopherol induces apoptosis in erythroleukemia, prostate, and breast cancer cells. Nutrition and Cancer, 28(1), 30-35.
135. Dabrosin, C., Chen, J., Wang, L., & Thompson, L.U. (2002). Flaxseed inhibits metastasis and decreases extracellular vascular endothelial growth factor in human breast cancer xenografts. Cancer Letters, 185(1), 31-37.
136. Demark-Wahnefried, W., Price, D.T., Polascik, T.J., Robertson, C.N., Anderson, E.E., Paulson, D.F., et al. (2001). Pilot study of dietary fat restriction and flaxseed supplementation in men with prostate cancer before surgery: exploring the effects on hormonal levels, prostatespecific antigen, and histopathologic features. Urology, 58(1), 47-52.
137. Denis, L., Morton, M.S., & Griffiths, K. (1999). Diet and its preventive role in prostatic disease. European Urology, 35(5-6), 377-387.
138. Lin, X., Gingrich, J.R., Bao, W., Li, J., Haroon, Z.A., Demark-Wahnefried, W., et al. (2002). Effect of flaxseed supplementation on prostatic carcinoma in transgenic mice. Urology, 60(5), 919-924.
139. Moyad, M.A. (2000). The ABCs of nutrition and supplements for prostate cancer. Ann Arbor, MI: JW Edwards Publishing.
140. Hsing, A.W., Chokkalingam, A.P., Gao, Y.T., Madigan, M.P., Deng, J., Gridley, G., et al. (2002). Allium vegetables and risk of prostate cancer: a population-based study. Journal of the National Cancer Institute, 94(21), 1648-1651.
141. Pinto, J.T., & Rivlin, R.S. (2001). Antiproliferative effects of allium derivatives from garlic. The Journal of Nutrition, 131(3s), 1058S-1060S.
142. Fleischauer, A.T., & Arab, L. (2001). Garlic and cancer: a critical review of the epidemiologic literature. The Journal of Nutrition, (3s), 1032S-1040S.
143. Vikse, R., Reistad, R., Steffensen, I.L., Paulsen, J.E., Nyholm, S.H., Alexander, J., et al. (1999). [Heterocyclic amines in cooked meat] [Article in Norwegian] Tidsskrift for den Norske Laegeforening, 119(1), 45-49.
144. Shirai, T., Imaida, K., & Ito, N. (2000). Prostate. In: M. Nagao and T. Sugimura (Eds.), Food Born Carcinogenesis. Current Toxicology Series, (pp. 270-274). Wiley, Chichester.
145. Shirai, T., Sano, M., Tamano, S., Takahashi, S., Hirose, M., Futakuchi, M., et al. (1997). The prostate: a target for carcinogenicity of 2- amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) derived from cooked foods. Cancer Research, 57, 195- 198.
146. Cui, L., Takahashi, S., Tada, M., Kato, K., Yamada, Y., Kohri, K., et al. (2000). Immunohistochemical detection of carcinogen-DNA adducts in normal human prostate tissues transplanted into the subcutis of athymic nude mice: Results with 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine (PhIP) and 3,2'-dimethyl-4-aminobiphenyl (DMAB) and relation to cytochrome P450s and N-acetyltransferase activity. Japanese Journal of Cancer Research, 91, 52- 58.
147. Nowell, S., Ratnasinghe, D.L., Ambrosone, C.B., Williams, S., Teague-Ross, T., Trimble L., et al. (2004). Association of SULT1A1 Phenotype and Genotype with Prostate Cancer Risk in African-Americans and Caucasians. Cancer Epidemiology Biomarkers Prevention, 13(2), 270-276.
148. Kooiman, G.G., Martin, F.L., Williams, J.A., Grover, P.L., Phillips, D.H., & Muir, G.H., et al. (2000). The influence of dietary and environmental factors on prostate cancer risk. Prostate Cancer Prostatic Diseases, 3(4), 256-258.
149. Hu, J.J., Hall, M.C., Grossman, L., Hedayati, M., McCullough, D.L., Lohman, K., et al. (2004). Deficient nucleotide excision repair capacity enhances human prostate cancer risk. Cancer Research, 64(3), 1197-1201.
150. Ferguson, L.R. (2002). Meat consumption, cancer risk and population groups within New Zealand. Mutation Research, 506-507, 215- 224.
151. Norrish, A.E., Ferguson, L.R., Knize, M.G., Felton, J.S., Sharpe, S.J., & Jackson R.T. (1999). Heterocyclic amine content of cooked meat and risk of prostate cancer. Journal of the National Cancer Institute, 91(23), 2038-2044.
152. Eder, E. (1999). Intraindividual variations of DNA adduct levels in humans. Mutation Research, 424(1-2), 249-261.
153. Bogen, K.T., & Keating, G.A. (2001). U.S. dietary exposures to heterocyclic amines. Journal of Exposure Anaysis & Environmental Epidemiology, (3), 155-168.
154. Wilkinson, G.R. (1997). The effects of diet, aging and disease-states on presystemic elimination and oral drug bioavailability in humans. Advance Drug Delivery Reviews, 27(2-3), 129-159.
155. Leone, M., Zhai, D., Sareth, S., Kitada, S., Reed, J.C., & Pellecchia, M. (2003). Cancer prevention by tea polyphenols is linked to their direct inhibition of antiapoptotic Bcl-2-family proteins. Cancer Research, 63(23), 8118-8121.
156. Saleem, M., Adhami, V.M., Siddiqui, I.A., & Mukhtar, H. (2003). Tea beverage in chemoprevention of prostate cancer: a mini-review. Nutrition Cancer, 47(1), 13-23.
157. Gupta, S., Hussain, T., & Mukhtar, H. (2003). Molecular pathway for (-)-epigallocatechin-3-gallate-induced cell cycle arrest and apoptosis of human prostate carcinoma cells. Archives of Biochemistry and Biophysics, 410(1), 177-185.
158. Jian, L., Xie, L.P., Lee, A.H., & Binns, C.W. (2004). Protective effect of green tea against prostate cancer: a case-control study in southeast China. International Journal of Cancer, 108(1), 130-135.
159. Yu, H.N., Yin, J.J., & Shen, S.R. (2004). Growth inhibition of prostate cancer cells by epigallocatechin gallate in the presence of Cu2+. Journal of Agricultural Food Chemistry, 52(3), 462-466.
160. Brusselmans, K., De Schrijver, E., Heyns, W., Verhoeven, G., & Swinnen, J.V. (2003). Epigallocatechin-3-gallate is a potent natural inhibitor of fatty acid synthase in intact cells and selectively induces apoptosis in prostate cancer cells. International Journal of Cancer, 106(6), 856-862.
161. Chung, L.Y., Cheung, T.C., Kong, S.K., Fung, K.P., Choy, Y.M., Chan, Z.Y., et al. (2001). Induction of apoptosis by green tea catechins in human prostate cancer DU145 cells. Life Sciences, 68(10), 1207-1214.
162. Hastak, K., Gupta, S., Ahmad, N., Agarwal, M.K., Agarwal, M.L., Mukhtar, H., et al. (2003). Role of p53 and NF-kappaB in epigallocatechin-3-gallate-induced apoptosis of LNCaP cells. Oncogene, 22(31), 4851-4859.
163. Gupta, S., Srivastava, M., Ahmad, N., Sakamoto, K., Bostwick, D.G., Mukhtar, H., et al. (2001). Lipoxygenase-5 is overexpressed in prostate adenocarcinoma. Cancer, 91(4), 737-743.
164. Zhou, J.R., Yu, L., Zhong, Y., & Blackburn, G.L. (2003). Soy phytochemicals and tea bioactive components synergistically inhibit androgen-sensitive human prostate tumors in mice. Journal of Nutrition, 133(2), 516-521.
165. Jatoi, A., Ellison, N., Burch, P.A., Sloan, J.A., Dakhil, S.R., Novotny, P., et al. (2003). A phase II trial of green tea in the treatment of patients with androgen independent metastatic prostate carcinoma. Cancer, 97(6), 1442-1446.
166. Jenkins, D.J., Kendall, C.W., D'Costa, M.A., Jackson, C.J., Vidgen, E., Singer W., et al. (2003). Soy consumption and phytoestrogens: effect on serum prostate specific antigen when blood lipids and oxidized low-density lipoprotein are reduced in hyperlipidemic men. Journal of Urology, 169(2), 507-511.
167. McCarty, M.F. (1999). Vegan proteins may reduce risk of cancer, obesity, and cardiovascular disease by promoting increased glucagon activity. Medical Hypotheses, 53(6), 459-485.
168. Arliss, R.M., & Biermann, C.A. (2002). Do soy isoflavones lower cholesterol, inhibit atherosclerosis, and play a role in cancer prevention? Holistic Nursing Practice, 16(5), 40-48.
169. Setchell, K.D., & Lydeking-Olsen, E. (2003). Dietary phytoestrogens and their effect on bone: evidence from in vitro and in vivo, human observational, and dietary intervention studies. American Journal of Clinical Nutrition, 78(3 Suppl), 593S-609S.
170. Ho, SC., Woo, J., Lam, S., Chen, Y., Sham, A., Lau, J., et al. (2003). Soy protein consumption and bone mass in early postmenopausal Chinese women. Osteoporosis International, 14(10), 835-842.
171. Messina, M.J., Persky, V., Setchell, K.D., & Barnes, S. (1994). Soy intake and cancer risk: a review of the in vitro and in vivo data. Nutrition Cancer, 21, 113-131.
172. Zhou, J.R., Yu, L., Zhong, Y., Nassr, R.L., Franke, A.A., Gaston S.M., et al. (2002). Inhibition of orthotopic growth and metastasis of androgen-sensitive human prostate tumors in mice by bioactive soybean components. Prostate, Oct 1, 53(2), 143-153.
173. Messina, M.J. (2003). Emerging evidence on the role of soy in reducing prostate cancer risk. Nutrition Reviews, 61(4), 117-131.
174. Pollard, M., & Wolter, W. (2000). Prevention of spontaneous prostate-related cancer in Lobund-Wistar rats by a soy protein isolate/ isoflavone diet. Prostate, 45(2), 101-105.
175. Jacobsen, B.K., Knutsen, S.F., & Fraser, G.E. (1998). Does high soy milk intake reduce prostate cancer incidence? The Adventist Health Study (United States). Cancer Causes & Control, 9, 553- 557.
176. Aronson, W.J., Tymchuk, C.N., Elashoff, R.M., McBride, W.H., McLean, C., Wang, H., et al. (1999). Decreased growth of human prostate LNCaP tumors in SCID mice fed a low-fat, soy protein diet with isoflavones. Nutrition and Cancer, 35(2), 130-136.
177. Yi, M.A., Son, H.M., Lee, J.S., Kwon, C.S., Lim, J.K., Yeo, Y.K., et al. (2002). Regulation of male sex hormone levels by soy isoflavones in rats. Nutrition & Cancer, 42(2), 206-210.
178. Gardner-Thorpe, D., O'Hagen, C., Young, I., & Lewis, S.J. (2003). Dietary supplements of soya flour lower serum testosterone concentrations and improve markers of oxidative stress in men. European Journal of Clinical Nutrition, 57(1), 100-106.
179. Tsutsumi, M., Suzuki, K., Shiga, Y., Ishikawa, S., & Ishikawa, Y. (2002). [A low-fat and high soybean protein diet for patients with elevated serum PSA level: alteration of QOL and serum PSA level after the dietary intervention] [Article in Japanese] Hinyokika Kiyo, 48(4), 207-211.
180. Getzenberg, R.H., Light, B.W., Lapco, B.W. Konety B.R., Nangia A.K., Acierno J.S., et al. (1997). Vitamin D inhibition of prostate adenocarcinoma growth and metastasis in the Dunning rat prostate model system. Urology, 50, 999- 1006.
181. Schwartz, G.G., Oeler, T.A., Uskokovic, M.R., & Bahnson, R.R. (1994). Human prostate cancer cells: inhibition of proliferation by vitamin D analogs. Anticancer Research, 14, 1077- 1081.
182. Lokeshwar, B.L., Schwartz, G.G., Selzer, M.G., Burnstein, K.L., Zhuang, S.H., & Block, N.L., et al. (1999). Inhibition of prostate cancer metastasis in vivo: a comparison of 1,23-dihydroxyvitamin D (calcitriol) and EB1089. Cancer Epidemiology Biomarkers Prevention, 8(3), 241-248.
183. Blutt, S.E., Polek, T.C., Stewart, L.V., Kattan, M.W., & Weigel, N.L. (2000). A calcitriol analogue, EB1089, inhibits the growth of LNCaP tumors in nude mice. Cancer Research, 60(4), 779-782.
184. Vegesna, V., O'Kelly, J., Said, J., Uskokovic, M., Binderup, L., Koeffle, H.P., et al. (2003). Ability of potent vitamin D3 analogs to inhibit growth of prostate cancer cells in vivo. Anticancer Research, 23(1A), 283-289.
185. Ahonen, M.H., Tenkanen, L., Teppo, L., Hakama, M., & Tuohimaa, P. (2000). Prostate cancer risk and prediagnostic serum 25- hydroxyvitamin D levels (Finland). Cancer Causes Control, 11(9), 847-852.
186. Tuohimaa, P., Tenkanen, L., Ahonen, M., Lumme, S., Jellum, E., Hallmans, G., et al. (2004). Both high and low levels of blood vitamin D are associated with a higher prostate cancer risk: a longitudinal, nested case-control study in the Nordic countries. International Journal of Cancer, 108(1), 104-108.
187. Peehl, D.M., Krishnan, A.V., & Feldman, D. (2003). Pathways mediating the growth-inhibitory actions of vitamin D in prostate cancer. Journal of Nutrition, 133(7 Suppl), 2461S-2469S.
188. Studzinski, G.P., & Moore, D.C. (1995). Sunlight--can it prevent as well as cause cancer? Cancer Research, 55(18), 4014-4022.
189. Gross, C., Stamey, T., Hancock, S., & Feldman, D. (1998). Treatment of early recurrent prostate cancer with 1,25-dihydroxyvitamin D3 (calcitriol) Journal of Urology, 159(6), 2035-2039.
190. Chen, T.C., Wang, L., Whitlatch, LW., Flanagan, J.N., & Holick, M.F. (2003). Prostatic 25-hydroxyvitamin D-1alpha-hydroxylase and its implication in prostate cancer. Journal of Cell Biochemistry, 88(2), 315-322.
191. Hanchette, C.L., & Schwartz, G.G. (1992). Geographic patterns of prostate cancer mortality. Evidence for a protective effect of ultraviolet radiation. Cancer, 70(12), 2861-2869.
192. Corder, E.H., Guess, H.A., Hulka, B.S., Friedman, G.D., Sadler, M., Vollmer, R.T., et al. (1993). Vitamin D and prostate cancer: a prediagnostic study with stored sera. Cancer Epidemiology, Biomarkers and Prevention, 2(5), 467-472.
193. Beer, T.M. (2003). Development of weekly high-dose calcitriol based therapy for prostate cancer. Urology Oncology, 21(5), 399-405.
194. Grant, W.B. (1999). An ecologic study of dietary links to prostate cancer. Alternative Medicine Reviews, (3), 162-169.
195. Gunnell, D., Oliver, S.E., Peters, T.J., Donovan, J.L., Persad, R., Maynard, M., et al. (2003). Are diet-prostate cancer associations mediated by the IGF axis? A cross-sectional analysis of diet, IGF-I and IGFBP-3 in healthy middle-aged men. British Journal of Cancer, 88(11), 1682-1686.
196. Holick, M.F. (1995). Defects in the synthesis and metabolism of vitamin D. Experimental Clinical Endocrinology Diabetes, 103(4), 219-227.
197. Thomas, M.K., Lloyd-Jones, D.M., Thadhani, R.I., Shaw, A.C., Deraska, D.J., Kitch, B.T., et al. (1998). Hypovitaminosis D in medical inpatients. New England Journal of Medicine, 338, 777-778.
198. Rasmussen, L.B., Hansen, G.L., Hansen, E., Koch, B., Mosekilde, L., Molgaard, C., et al. (2000). Vitamin D: should the supply in the Danish population be increased? International Journal of Food Science Nutrition, 51(3), 209-215.
199. Webb, A.R., Pilbeam, C., Hanafin, N., & Holick, M.F. (1990). An evaluation of the relative contributions of exposure to sunlight and of diet to the circulating concentrations of 25-hydroxyvitamin D in an elderly nursing home population in Boston. American Journal of Clinical Nutrition, 51, 1075- 1081.
200. Silverberg, S.J., Shane, E., dela Cruz, L., Segre, C.V., Clemens, T.L., Bilezikian, J.P., et al. (1989). Vitamin D hydroxylation abnormalities in parathyroid hormone secretion and 1,25-dihydroxyvitamin D-3 formation in women with osteoporosis. New England Journal of Medicine, 320, 277- 281.
201. Ebeling, P.R., Sandgren, M.E., DiMagno, E.P., Lane, A.W., DeLuca, H.F., Riggs B.L., et al. (1992). Evidence of an age-related decrease in intestinal responsiveness to vitamin D: relationship between serum 1,25-dihydroxyvitamin D-3 and intestinal vitamin D receptor concentrations in normal women. Journal of Clinical Endocrinology Metabolism, 75, 176- 182.
202.V Singh, R.P., & Agarwal, R. (2004. Prostate cancer prevention by silibinin. Current Cancer Drug Targets, 4(1), 1-11.
203. Singh, R.P., Dhanalakshmi, S., Tyagi, A.K., Chan, D.C., Agarwal, C., & Agarwal, R. (2002). Dietary feeding of silibinin inhibits advance human prostate carcinoma growth in athymic nude mice and increases plasma insulin-like growth factor-binding protein-3 levels. Cancer Research, 62(11), 3063-3069.
204. Tyagi, A., Bhatia, N., Condon, M.S., Bosland, M.C., Agarwal, C., & Agarwal, R. (2002). Antiproliferative and apoptotic effects of silibinin in rat prostate cancer cells. Prostate, 53(3), 211-217.
205. Tyagi, A.K., Singh, R.P., Agarwal, C., Chan, D.C., & Agarwal, R. (2002). Silibinin strongly synergizes human prostate carcinoma DU145 cells to doxorubicin-induced growth Inhibition, G2-M arrest, and apoptosis. Clinical Cancer Research, 8(11), 3512-3519.
206. Zi, X., Zhang, J., Agarwal, R., & Pollak, M. (2000). Silibinin up-regulates insulin-like growth factor-binding protein 3 expression and inhibits proliferation of androgen-independent prostate cancer cells. Cancer Research, 60(20), 5617-5620.
207. Cordell, G.A. (2002). PC-SPES: a brief overview. Integrative Cancer Therapies, 1(3), 271-286.
208. Yip, I., Cudiamat, M., & Chim, D. (2003). PC-SPES for treatment of prostate cancer: herbal medicine. Current Urology Reports, 4(3), 253-257.
209. Katz, A.E. (2002). Flavonoid and botanical approaches to prostate health. Journal of Alternative and Complementary Medicine, 8(6), 813-821.
210. Goldmann, W.H., Sharma, A.L., Currier, S.J., Johnston, P.D., Rana, A., & Sharma, C.P. (2001). Saw palmetto berry extract inhibits cell growth and Cox-2 expression in prostatic cancer cells. Cell Biology International, 25(11), 1117-1124.
211. Dorai, T., Cao, Y.C., Dorai, B., Buttyan, R., & Katz, A.E. (2001). Therapeutic potential of curcumin in human prostate cancer. III. Curcumin inhibits proliferation, induces apoptosis, and inhibits angiogenesis of LNCaP prostate cancer cells in vivo. Prostate, 47(4), 293-303.
212. Dorai, T., Gehani, N., & Katz, A. (2000). Therapeutic potential of curcumin in human prostate cancer. II. Curcumin inhibits tyrosine kinase activity of epidermal growth factor receptor and depletes the protein. Molecular Urology, 4(1), 1-6.
213. Deeb, D., Xu, Y.X., Jiang, H., Gao, X., Janakiraman, N., Chapman, RA., et al. (2003). Curcumin (diferuloyl-methane) enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in LNCaP prostate cancer cells. Molecular Cancer Therapeutics, 2(1), 95-103.
214. Chendil, D., Ranga, R.S., Meigooni, D., Sathishkumar, S., & Ahmed, M.M. (2004). Curcumin confers radiosensitizing effect in prostate cancer cell line PC-3. Oncogene, 23(8), 1599-1607.
215. Huang, M.T., Lou, Y.R., Xie, J.G., Ma, W., Lu, Y.P., Yen, P., et al. (1998). Effect of dietary curcumin and dibenzoylmethane on formation of 7,12-dimethylbenz[a]anthracene-induced mammary tumors and lymphomas/leukemias in Sencar mice. Carcinogenesis, 19(9), 1697-1700.
216. Wallace, J.M. (2002). Nutritional and botanical modulation of the inflammatory cascade--eicosanoids, cyclooxygenases, and lipoxygenases--as an adjunct in cancer therapy. Integrative Cancer Therapies, 1(1), 7-37.

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